Several general principles have emerged from the study of human transcription factors. First, germline mutations in genes encoding transcription factors result
This work discusses the basic science of transcriptional regulation, and describes inherited human diseases attributable to mutations in DNA sequences encoding
A much-needed guide through the overwhelming amount of literature in the field. Comprehensive and detailed, this book combines background information with the m
In the last few years, significant breakthroughs in transcription research expanded our appreciation for the complexity of molecular controls on gene expression
In Gene Regulatory Sequences and Human Disease, the Editor will introduce the different technological advances that led to this breakthrough. In addition, sever