Target Organ Toxicity
Author | : Cohen |
Publisher | : CRC Press |
Total Pages | : 246 |
Release | : 1986-08-31 |
ISBN-10 | : 0849357756 |
ISBN-13 | : 9780849357756 |
Rating | : 4/5 (56 Downloads) |
Download or read book Target Organ Toxicity written by Cohen and published by CRC Press. This book was released on 1986-08-31 with total page 246 pages. Available in PDF, EPUB and Kindle. Book excerpt: This two-volume set provides essential information on the general princi-ples of target organ toxicity. Pharmacokinetics, metabolic activation and key defense mechanisms, excretion, species variation, and tissue-specific biochemistry are explored comprehensively. These general principles are then illustrated using specific examples of toxicity to different target organs and systems. DNA modifi-cation and repair in tumor induction, and specificity in tumor initiation are also examined. Of primary interest to toxicologist, pharma-cologists, biochemists, and environmental toxicologists.