Exploring an Emerging Technique of Nanotechnology in Vaccine Design and Manufacturing to combat SARS-CoV-2.

Download or read book Exploring an Emerging Technique of Nanotechnology in Vaccine Design and Manufacturing to combat SARS-CoV-2. written by Dr. Hakim. Saboowala. and published by Dr.Hakim Saboowala. This book was released on with total page 69 pages. Available in PDF, EPUB and Kindle. Book excerpt: Exploring an Emerging Technique of Nanotechnology in Vaccine Design and Manufacturing to combat SARS-CoV-2. Nanoparticles are loosely defined as nanoscale-sized and tunable particulate structures that mimic structural features of natural viruses. Besides traditional vaccine modalities and DNA and vector-based vaccines, nanoparticle vaccines offer a unique opportunity to advance vaccine science and provide tractable solutions to the current pandemic and beyond. This adaptive design makes them highly promising platforms for next-generation vaccine development, providing pathways to drive strong nAb responses, or broader antibody-based immunity that might better account for variation and evolution of viral pathogens. COVID-19 has become a major cause of global mortality and driven massive health and economic disruptions. At present, over 26 nanoparticle vaccine candidates have advanced into clinical testing, with ∼60 more in pre-clinical development. Hence an attempt has been made in this Booklet to explore the emerging technique of nanotechnology in vaccine design and manufacturing to combat SARS-CoV-2, and highlight opportunities and challenges presented by these novel vaccine platforms. …Dr. H. K. Saboowala. M.B.(Bom) .M.R.S.H.(London)