This book provides statisticians and researchers with the statistical tools - equations, formulae and numerical tables - to design and plan clinical studies and

Praise for the Second Edition: "... this is a useful, comprehensive compendium of almost every possible sample size formula. The strong organization and careful

Drawing on various real-world applications, Sample Sizes for Clinical Trials takes readers through the process of calculating sample sizes for many types of cli

An authoritative resource that offers the statistical tools and software needed to design and plan valid clinical studies Now in its fourth and extended edition

Sample size calculation plays an important role in clinical research. It is not uncommon, however, to observe discrepancies among study objectives (or hypothese