Immune Correlates of Protection for Emerging Diseases – Lessons from Ebola and COVID-19

Download or read book Immune Correlates of Protection for Emerging Diseases – Lessons from Ebola and COVID-19 written by Javier Castillo-Olivares and published by Frontiers Media SA. This book was released on 2024-04-08 with total page 279 pages. Available in PDF, EPUB and Kindle. Book excerpt: Correlates of Protection (CoP) are biological parameters present in vaccinated or naturally infected individuals that predict levels of protection against an infectious disease. CoP facilitate vaccine licensing since they enable: a) the selection of antigen composition of a vaccine; b) the assessment of vaccine efficacy in clinical trials without exposure of participants to natural infection; and c) bridging between first- and second-generation vaccines.