Chemosensitivity Testing in Oncology

Chemosensitivity Testing in Oncology
Author :
Publisher : Springer Science & Business Media
Total Pages : 262
Release :
ISBN-10 : 9783642190223
ISBN-13 : 3642190227
Rating : 4/5 (23 Downloads)

Book Synopsis Chemosensitivity Testing in Oncology by : Uwe Reinhold

Download or read book Chemosensitivity Testing in Oncology written by Uwe Reinhold and published by Springer Science & Business Media. This book was released on 2012-12-06 with total page 262 pages. Available in PDF, EPUB and Kindle. Book excerpt: Over the past 50 years many in vitro and in vivo drug response assay systems have been developed to determine the potential - tivity of chemotherapy agents. The idea was to eliminate ineffective agents and unnecessary toxic treatment while selecting drugs active in vitro or in the mouse model that might increase the probability of response in the patient. None of these test models, however, achieved routine clinical application in the past. This might be at least in part - lated to large discrepancies that were described between the s- cess rate of the assay systems and the clinical benefit in cancer - tients. The heterogeneity of chemosensitivity that exists between different tumors as well as between individual tumor lesions may be one explanation for these findings. Furthermore, different assay end points such as proliferation, metabolism, and vitality were - veloped to evaluate the effects of cytostatic drugs on tumor cells, and these might be related to the differing results. However, knowledge about procedures for assay-assisted treatment selection has increased rapidly within the past few years, and several studies suggest that test-directed chemotherapy selection now may - prove response rates and survival in various types of tumors. The International Society for Chemosensitivity Testing in - cology (ISCO) was founded to promote, coordinate, and improve clinical and laboratory research in the field of predictive drug te- ing in human tumor cells.


Chemosensitivity Testing in Oncology Related Books

Chemosensitivity Testing in Oncology
Language: en
Pages: 262
Authors: Uwe Reinhold
Categories: Medical
Type: BOOK - Published: 2012-12-06 - Publisher: Springer Science & Business Media

DOWNLOAD EBOOK

Over the past 50 years many in vitro and in vivo drug response assay systems have been developed to determine the potential - tivity of chemotherapy agents. The
Chemosensitivity
Language: en
Pages: 234
Authors: Rosalyn D. Blumenthal
Categories: Medical
Type: BOOK - Published: 2008-02-01 - Publisher: Springer Science & Business Media

DOWNLOAD EBOOK

A state-of-the art collection of readily reproducible laboratory methods for assessing chemosensitivity in vitro and in vivo, and for assessing the parameters t
Augmentation of Peripheral Chemosensitivity During Hypermetabolism
Language: en
Pages: 361
Authors: Ismaeel Bin-Jaliah
Categories: Medical
Type: BOOK - Published: 2006 - Publisher: Universal-Publishers

DOWNLOAD EBOOK

The carotid body initiates reflexes aimed principally at the homeostatic maintenance of blood gas tensions. This thesis tested the hypothesis that the carotid b
Breast Cancer Chemosensitivity
Language: en
Pages: 175
Authors: Dihua Yu
Categories: Medical
Type: BOOK - Published: 2009-12-30 - Publisher: Springer Science & Business Media

DOWNLOAD EBOOK

In Breast Cancer Chemosensitivity, a group of world leading experts review critical aspects of resistance to systemic therapy in breast cancer patients. Beginni
Chemosensitivity Testing in Gynecologic Malignancies and Breast Cancer
Language: en
Pages: 218
Authors: Ossi R. Köchli
Categories: Medical
Type: BOOK - Published: 1994 - Publisher: S. Karger AG (Switzerland)

DOWNLOAD EBOOK

'It will form an important addition to a scientific library and a useful addition to the (contributions series) which should be part of any obstetrics and gynae