Biology of Mesenchymal Stromal Cells -Emerging New Concepts to Improve Function and Scalability

Download or read book Biology of Mesenchymal Stromal Cells -Emerging New Concepts to Improve Function and Scalability written by Tokiko Nagamura-Inoue and published by Frontiers Media SA. This book was released on 2024-10-28 with total page 171 pages. Available in PDF, EPUB and Kindle. Book excerpt: Human mesenchymal stromal cells (MSCs) can be harvested from many tissues, including bone marrow (BM), cord blood (CB), adipose tissue, umbilical cord (UC), placenta and others. In recent years, there has been an overwhelming interest in MSC as reflected in the number of reports regarding their characterization, biological properties and clinical application. One of the specific areas of research involves the characterization of MSCs derived from different sources as well as the potential differences between them. More recently, reports have been published on derivatives from MSCs such as extracellular vesicles (EVs)/exosomes and mitochondria, but their characterization, mechanisms of action in immunomodulatory functions and regeneration aspects have not been fully elucidated.