For over fifty years the Methods in Enzymology series has been the critically acclaimed laboratory standard and one of the most respected publications in the fi

The ability of cells to sense and respond to changes in oxygenation underlies a multitude of developmental, physiological, and pathological processes. This volu

This presentation describes various aspects of the regulation of tissue oxygenation, including the roles of the circulatory system, respiratory system, and bloo

During the last ten years, knowledge about the multitude of adaptive responses of plants to low oxygen stress has grown immensely. The oxygen sensor mechanism h

In this volume, the authors will describe the mechanisms of hypoxia and angiogenesis from a systems perspective. Hypoxia – defined as low oxygen – is quanti