This document provides the second edition of Guidance Document 23 on Aqueous-Phase Aquatic Toxicity Testing of Difficult Test Chemicals.

This document provides guidance for the testing of substances, and mixtures, classed as “difficult to test” for the purposes of determining their aquatic to

In the past several decades, there has been a substantial increase in the availability of in vitro test methods for evaluating chemical safety in an internation

This document provides a description of a Harmonised System for the Classification of Chemicals which are Hazardous for the Aquatic Environment and guidance to

This document sets out the objectives, organisational context, and plan for a Harmonised Integrated Classification System for Human Health and Environmental Haz